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Spravato (Esketamine) Intra-Nasal Depression Medication
SPRAVATO® is a prescription medicine used:
-
with or without an antidepressant taken by mouth, to treat adults with treatment-resistant depression (TRD)
-
with an antidepressant taken by mouth, to treat depressive symptoms in adults with major depressive disorder (MDD) with suicidal thoughts or actions
SPRAVATO® is an NMDA
receptor antagonist believed to work differently from traditional antidepressants by acting on
glutamate
.
-
The exact way SPRAVATO® works is unknown.
While the exact role of glutamate in depression is unknown, it is a chemical messenger found in the brain that is thought to help balance well-being and depression.
How Does It Work?
You will administer SPRAVATO® nasal spray yourself under the supervision of a healthcare provider at a certified SPRAVATO® treatment center. Your healthcare provider will show you how to use the SPRAVATO® nasal spray device.

*Random Drug Screening for Controlled Substances is Required.
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